GENUS NAME: loperamide
Trade names: Imodium AD, antidiarrheal, TH Antidiarrheal, Diamode
DISCONTINUED manufacturers: Imodium, Kaopectate II A D, Maalox antidiarrheal Caplets, Pepto Diarrhea Management.
DRUG course AND MECHANISM: Loperamide is a drug that’s used for alleviation of diarrhea as well as the management of persistent diarrhea in-patients with inflammatory bowel disease (Crohn’s disease and ulcerative colitis). The potency of loperamide can be compared to still another antidiarrheal, diphenoxylate (Lomotil). Loperamide decreases diarrhea by slowing of the contents from the muscles. Although loperamide is linked chemically to narcotics like morphine, it does not possess any of narcotics’ pain- alleviating effects at large doses.

Imodium Side Effects

Loperamide is usually well-taken. The negative effects which were reported during loperamide therapy comprise:

Stomach pain,
Dry mouth,
And nausea,

Imodium Dosage

In kids 12 years old and older, the most common dose is 4 mg initially, followed by 2 mg after each loose stool. The most dose is-16 mg/day (8 mg if self-medicating).
For long-term diarrhea 4-8 milligrams daily could be administered after control is attained.
The dose for acute diarrhea in kids is: age eight to 1 2 years, 2 milligrams three times the initial day; age 6 to 8 years, 2 milligrams twice the initial day; age 2 to five years, 1 mg 3 times the initial day. Following the very first day, kids less than 12 years of age typically be given a dose of 0.1 mg/kg after a free stool.

Persistent diarrhea in kids is treated with 0.08-0.24 mg/kg/d split in to two doses, one-dose given every 1 2 hrs. For traveler’s diarrhea kids 6-12 years old obtain 2 mg following the first lose fecal matter subsequently 1 mg after each following fecal matter. Kids older than 1 2 receive 4 mg initially then 1 mg.

The optimum daily dose for traveler’s diarrhea is 4 milligrams (6-8 years aged), 6 milligrams (6-12 years aged), and 8 milligrams (>1 2 years aged).