Clarithromycin is a semi-synthetic macrolide antibiotic.
Streptococcus pyogenes ( The typical medicine to choose in the treatment and prevention of streptococcal bacterial infections along with the prophylaxis of rheumatic fever is penicillin administered by either the intramuscular or the oral route . Clarithromycin is mostly useful in the elimination of S . pyogenes from the nasopharynx ; although , data establishing the efficacy of clarithromycin in the future protection of rheumatic fever are not available presently ) .
Acute maxillary sinusitis because of Haemophilus influenzae, Moraxella catarrhalis, or Streptococcus pneumoniae.
Acute bacterial exacerbation of chronic bronchitis because of Haemophilus influenzae , Haemophilus parainfluenzae, Moraxella catarrhalis , or Streptococcus pneumoniae .
Community-Acquired Pneumonia because of Haemophilus influenzae , Mycoplasma pneumoniae , Streptococcus pneumoniae , or Chlamydia pneumoniae ( TWAR ) .
Uncomplicated skin and skin structure infections because of Staphylococcus aureus, or Streptococcus pyogenes ( Abscesses generally need surgical drainage ) .
Disseminated mycobacterial infections because of Mycobacterium avium , or Mycobacterium intracellulare
BIAXIN ( clarithromycin ) Filmtab pills combined with amoxicillin and PREVACID (lansoprazole) or PRILOSEC (omeprazole) Delayed-Release Capsules , as 3 times the treatment , are mentioned for the therapy of patients with H . pylori infection and duodenal ulcer illness ( active or five-year history of duodenal ulcer ) to eliminate H . pylori.
BIAXIN Filmtab pills combined with PRILOSEC (omeprazole) capsules or TRITEC (ranitidine bismuth citrate) pills are likewise indicated for the therapy of patients with a strong duodenal ulcer associated with H . pylori infection . Although , regimens that contain clarithromycin as the single antimicrobial agent usually tend to be related to the growth of clarithromycin resistance among patients who fail treatment . Clarithromycin-containing regimens ought not to be utilized in patients with known or suspected clarithromycin resistant isolates mainly because the efficacy of therapy decreased within this setting.
Biaxin (Clarithromycin) – Side Effects and Adverse Reactions
The most of side effects seen in medical tests were of a gentle and transient nature . Less than 3% of adult patients without mycobacterial infections and less than 2% of pediatric patients without mycobacterial infections withdrawn treatment due to drug-related side effects . Less than 2% of adult patients using BIAXIN XL tablets withdrawn treatment due to drug-related side effects .
The most often reported events in older people using BIAXIN tablets ( clarithromycin tablets , USP ) were diarrhea ( 3% ) , queasiness ( 3% ) , abnormal taste ( 3% ) , dyspepsia ( 2% ) , abdominal pain/discomfort ( 2% ) , and headaches ( 2% ) . In pediatric patients , the most often reported events were diarrhea ( 6% ) , nausea or vomiting ( 6% ) , abdominal ache ( 3% ) , rash ( 3% ) , and headaches ( 2% ) . Many of these events were classed as mild or moderate in seriousness . Of the reported adverse events , merely 1% was referred to as serious .
Biaxin (Clarithromycin) – Indications and Dosage
BIAXIN Filmtab (clarithromycin pills , USP) and BIAXIN Granules (clarithromycin for oral suspensions , USP) are suggested for the therapy of mild to moderate infections a result of susceptible isolates of the specified bacteria in the problems as listed here :
Pharyngitis/Tonsillitis because of Streptococcus pyogenes (The usual medicine of choice in the therapy and prevention of streptococcal bacterial infections along with the prophylaxis of rheumatic fever is penicillin prescribed by either the intramuscular or the oral route . Clarithromycin is usually useful in the eradication of S . pyogenes from the nasopharynx ; although , data establishing the efficacy of clarithromycin in the future prevention of rheumatic fever are not available at present) .
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