Seroquel is the brand of the generic drug quetiapine, used to treat schizophrenia and major affective disorder (formerly called manic-depression).
Seroquel changes the degree of neurotransmitters (naturally occurring brain substances) as well as serotonin and dopamine.
Seroquel belongs to a category of medicines referred to as atypical antipsychotics.
The Food and Drug Administration (FDA) approved quetiapine in 1997 as the brand Seroquel for drug manufacturer AstraZeneca.

Side Effects

Weight gain is a well-known side effect of taking Seroquel, and doctors have prescribed the drug off-label to treat anorexia. However, a study printed in European Eating Disorders Review in 2012 found that Seroquel failed to help folks with eating disorder gain weight, nor did it help ease their symptoms of anxiety or depression.

Moreover, there’s not enough proof to indicate that the advantages of Seroquel for off-label uses outweigh the risks related to the drug, finished a study printed in the Journal of Psychosocial Nursing and Mental Health Services in 2013.

Let your doctor know of any side effects you experience. Common side effects of Seroqual include:
• Dry mouth
• Sleepiness
• Dizziness
• Constipation
• Indigestion

Other side effects of Seroquel might include:
• Headache
• Body pains
• Weakness
• Vomiting
• Stuffy nose
• Irritability
• Trouble concentrating, thinking, or speaking clearly
• Clumsiness
• Unusual dreams
• Loss of interest in sex
• Breast enlargement in men
• Missed menstruation periods in ladies
• Nipple discharge

Serious side effects include:
• Fainting
• Seizures
• Uncontrollable body movements
• Painful erection that will not abate
• Fever with muscle stiffness, sweating, and weakness
• Unusual hemorrhage
• Irregular heartbeat
• Swelling of the face, lips, or tongue
• Severe rash, hives, or skin blistering


The Food and Drug Administration has warned that:
First, you must not take Seroquel if you’re an older person with dementia, a mental health condition that causes weakened memory, confused thinking, and changes in mood and temperament.

People with dementia have a multiplied risk for dying while on Seroquel. If you or a loved one might have dementia, speak with a specialist before taking Seroquel.

Secondly, Seroquel might increase your risk for suicide. The danger is greatest when beginning treatment or increasing the dose of Seroquel, and may be higher for individuals younger than 24 years.

Let your doctor know if you have any of these side effects whilst on medication:
• Thoughts of suicide
• Worsening depression
• Symptoms of aggression
• Irritability
• Panic attacks
• Restlessness
• Acting stupidly

Your doctor will watch you carefully for any of these symptoms after you begin Seroquel. Also, let your friends and relations understand these symptoms.
Experts do not know whether or not Seroquel may be a safe and effective treatment for schizophrenia in children younger than 13 years.
The safety of the drug for treating bipolar mania in kids younger than 10 years and bipolar depression in kids younger than 18 years is equally unknown.
When taking Seroquel, you must avoid extreme exercise, particularly in hot weather.

Drink lots of water, particularly when you are having a workout or out in hot weather.

Do not stop taking this drug suddenly, because it will cause withdrawal symptoms as well as nausea, vomiting, and sleep disorders.
Seroquel might increase your risk for diabetes, therefore tell your doctor about any history of diabetes in you or your family.
Also, ask your doctor what symptoms of diabetes to watch for while you’re on Seroquel.


Adult dose for schizophrenia might vary from 150 to 750 milligrams (mg) on a daily basis.
Adult dose for bipolar disorder might vary from 400 to 800 mg each day.
Your doctor can begin you at a low dose then bit by bit increase your dose till your symptoms improve.
You can take Seroquel with or without food. Take the tablets whole with a glass of water. Don’t split or crush them.


Ingesting 13.6 grams of Seroquel has resulted in a very fatal overdose. Symptoms of a Seroquel overdose might include:
• Vomiting
• Drowsiness
• Rapid heartbeat
• Dizziness
• Seizure
• Fainting

If you or somebody you know has symptoms of an overdose, contact emergency service immediately

Missed Dose

Take Seroquel precisely as directed by your doctor. If you miss a dose of Seroquel, take the missed dose immediately you remember. If it’s almost time for your next dose, skip the missed dose. Don’t take double dose to make up for a missed dose.